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JNJ-64619178

Recent Publication

pseudo-irreversible methyltransferase inh.

oral, phase I, cancer

from adenosine derivative library + opt.

Molecular Cancer Therapeutics

Janssen R&D

The Janssen PRMT5 inhibitor, onametostat (JNJ-64619178) is a selective, orally active and pseudo-irreversible protein arginine methyltransferase 5 (PRMT5) inhibitor with high selectivity and potency (subnanomolar range, PRMT5-MEP-50 IC50=0.14 nM) under various…

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JNJ-64619178

this content is exclusive to Premium members

this content is exclusive to
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