© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
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G-protein biased GPCR agonist
oral 10 mg QD, phase I, cardiovascular
from HTS and opt.
The Sanofi S1P1 agonist, SAR247799, is a biased agonist of the S1P1 sphingosine receptor, preferentially activating G-protein signaling over the β-arrestin and internalization pathways. Commercial S1P1 modulators such as fingolimod…
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