6. BMS-986318 – BMS cyclobutene-containing FXR agonist

Small Molecules of the Month – Aug. 2021

The August edition of Small Molecules of the Month, features a recently approved, dibasic oral kallikrein inhibitor, a spirocyclobutene-containing FXR agonist, a NaV1.6 clinical candidate, a remarkably long acting RIPK2 PROTAC, and several other interesting clinical candidates. Thanks to reviewers …

Small Molecules of the Month – Jul. 2021

Thanks to our featured reviewers for their feedback, with special thanks to neuroscience reviewer Jake Schwarz for feedback and commentary on an unusual 5 neuroscience molecules this month. July’s edition of Small Molecules of the Month, features a selective monovalent …