Chemical structure of molecule Milvexian BMS-986177

selective factor Xia serine protease inhib.

oral, phase II, cardiovascular

from opt. of previous macrocyclic FXIa inh.

Journal of Medicinal Chemistry

Bristol Myers Squibb

The BMS factor XIa inhibitor, milvexian (BMS-986177), is an oral antithrombotic with a Ki of 0.11 nM. A member of this macrocyclic series was previously highlighted as one of 2020’s Molecules of…

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