selective factor Xia serine protease inhib.

oral, phase II, cardiovascular

from opt. of previous macrocyclic FXIa inh.

Journal of Medicinal Chemistry

Bristol Myers Squibb

Chemical structure of molecule Milvexian BMS-986177

The BMS factor XIa inhibitor, milvexian (BMS-986177), is an oral antithrombotic with a Ki of 0.11 nM. A member of this macrocyclic series was previously highlighted as one of 2020’s Molecules of…


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