potent and selective Mcl-1 PPI inhibitor
completed Ph. I in AML/MDS (IV weekly)
from NMR fragment screening and SBDD
J. Med. Chem., Nov. 4, 2020
Servier, HU + FR / Vernalis, UK
S64315
1 min read
Servier selective clinical Mcl-1 protein-protein interaction (PPI) inhibitor
Search By Structure
- LY3502970
- S64315
- daridorexant
- “peptide 78”
- BMS-986144
- MLT-985
- EB-42486
- “compound 4d”
- “compound 60b”
- “compound 15a”
- “compound 31”
- “compound 36”
- BCPyr
- “compound 4j”
Molecules of the Month
2023
2022
2021
2020