oral G2019S-LRRK2 mut.-selective kinase inh.
>70x sel. for ParkinsonÕs mut. over WT, non-BP
from 50k cmpd HTS + homology-based opt.
J. Med. Chem., Nov. 16, 2020
ESCAPE Bio, South San Francisco, CA
EB-42486
1 min read
EB-42486 (ESCAPE Bio oral G2019S-LRRK2 mutant-selective kinase inhibitor)
Search By Structure
- LY3502970
- S64315
- daridorexant
- “peptide 78”
- BMS-986144
- MLT-985
- EB-42486
- “compound 4d”
- “compound 60b”
- “compound 15a”
- “compound 31”
- “compound 36”
- BCPyr
- “compound 4j”
Molecules of the Month
2023
2022
2021
2020