With the all the newsflow on drug re-purposing for the coronavirus, it’s easy to overlook all the interesting drug discovery articles that have been published in March. A summary of some of the most interesting compounds that appeared online this month appears below, and links to the original articles are at the bottom. Two molecules with degrader mechanisms that demonstrated compelling in vivo activity made this month’s list, and a flurry of excellent molecules intended for hot (or once hot) oncology targets appeared as well.
Molecules of the Month
March 2020
- CC-92480
- “PROTAC 6”
- GSK620
- Merck hArg1 inhibitor
- Merck IDO1 inhibitor
- Constellation EZH2 inhibitor
- Arcus CD73 inhibitor
- MK-6884
- sulfopin
- M3814
- remibrutinib
Molecules of the Month
Molecules of the Month
Nominate a molecule
Saw an interesting case study recently? Share it with the community!
Become a reviewer
Interested in helping assess new topics and providing scientific input? Get connected!
Join the Drug Hunter Mailing List
to get free content and resources weekly. Trusted by >15,000 drug hunters worldwide. Unsubscribe anytime.
Popular Content
- 1.2023 Novel Small Molecule FDA Drug Approvals
- 2.Top 12 Most Popular Drug Hunter Case Studies of 2023
- 3.Top Ten Most Popular Drug Hunter Resources of 2023
- 4.Top 10 Most Popular Drug Hunter Review Articles of 2023
- 5.Practical PK Calculators
- 6.AACR Orlando 2023: New Drug Candidates
- 7.PK Cheat Sheet
- 8.Phase I Drug Metabolism
- 9.Why pKas Matter in Medicinal Chemistry and a Drug Discovery Amine pKa Table
- 10.Phase II Drug Metabolism
- 11.First Disclosures from ACS Chicago 2022
- 12.Topliss Tree and Topliss Scheme Posters
VIEW MORE CONTENT