Chemical Structure of molecule Pamiparib inhibitor

oral, brain-penetrant PARP1/2 inh./DNA trap.

in Ph. III for maint. in ovarian + gastric cancer

ligand-based design from lit. PARPi

J. Med. Chem., Dec. 2, 2020

Beigene, Beijing, CN

Beigene oral, brain-penetrant PARP1/2 inhibitor/DNA trapping agent

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