oral, brain-penetrant PARP1/2 inh./DNA trap.
in Ph. III for maint. in ovarian + gastric cancer
ligand-based design from lit. PARPi
J. Med. Chem., Dec. 2, 2020
Beigene, Beijing, CN
pamiparib
Beigene oral, brain-penetrant PARP1/2 inhibitor/DNA trapping agent