oral noncovalent hemoglobin (HbS) modulator

2:1 binding, high RBC partition.; in Ph. I w/ HV

from virtual screening, NMR confirm. and opt.

J. Med. Chem., Dec. 24, 2020

Pfizer, Groton, CT / Cambridge, MA

Structure of PF07059013

Pfizer noncovalent oral hemoglobin (HbS) modulator

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