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molecules of the month

ACT-1004-1239

CXCR7 GPCR insurmountable antagonist

target engagement in rodent, 61% F in dog

from 300k HTS vs. _-arrestin recruitment, opt.

J. Med. Chem., Dec. 14, 2020

Idorsia Pharma (Actelion), Allschwil, CH

Chemical structure of molecule ACT-1004-1239
1 min read

Idorsia/Actelion CXCR7 GPCR insurmountable antagonist


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