MK-1454 (Merck) is an intratumoral stimulator of interferon (IFN) genes (STING) agonist that is being developed for treatment of advanced solid tumors and lymphomas. The molecule follows Aduro’s ADU-S100 , which was terminated after Ph. II due to [...]
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Apr. 19, 2022
MK-1454: An Intratumoral Stimulator of Interferon (IFN) Genes (STING) Agonist
ulevostinag (MK-1454)
intratumoral STING agonist in Ph. II for met. HNSCC cyclic dinucleotide derivative J. Med. Chem., March 25, 2022 Merck, Kenilworth, NJ
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