CRBN-based GSPT1 molecular glue degrader
intravenous agent in Ph. I for AML + MDS
from phenotypic screen of CRBN mod library
J. Med. Chem., Feb. 16, 2021
Celgene/Bristol Myers Squibb, San Diego, CA
CC-90009
1. The Bristol Myers Squibb (BMS)/Celgene GSPT1 degrader (CC-90009) is a CRBN-based molecular glue (CELMoD). It is a clinical candidate in Ph. I for AML and MDS, and in…