pan-serotype dengue virus NS4B inhibitor

oral preclin. candidate, trial planned

From 1.5M cmpd phenotypic screen + opt.

Sci. Transl. Med., Feb. 3, 2021

Novartis (NITD), Emeryville, CA


14. The Novartis pan-serotype dengue virus (DENV) NS4B protein inhibitor, NITD-688, is a preclinical candidate with strong activity against all four serotypes of DENV in vitro and excellent oral…

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