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PD-L1 inhibitor via induced internalization
oral activity (10 mpk QD) in humanized model
from biochemical HTRF screening
Nat. Comm., Feb. 22, 2021
Arbutus Biopharma Inc, Warminster, P
7. The Arbutus PD-L1 inhibitor ARB-272572 is a preclinical molecule that potently induces PD-L1 dimerization and internalization and demonstrates oral activity (10 mg/kg QD) in a humanized mouse model.…
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