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Nov. 3, 2021

EC5026: An Oral Soluble Epoxide Hydrolase Inhibitor


pM oral sEH epoxide hydrolase inhibitor completed Ph. I HV study + in animal health epoxide-opening transition-state mimic J. Med. Chem., Feb. 7, 2021 EicOsis Human Health Inc., Davis, CA

Drug Hunter Team

The EicOsis oral soluble epoxide hydrolase (sEH) inhibitor, EC5026, is a compound currently intended as a non-opioid analgesic and anti-inflammatory agent. It recently completed a Ph. I study in healthy volunteers without drug-related adverse events. Despite its small size, it has picomolar binding activity with the urea acting as an [...]



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