Chemical structure of molecule ARB-272572 inhibitor

PD-L1 inhibitor via induced internalization

oral activity (10 mpk QD) in humanized model

from biochemical HTRF screening

Nat. Comm., Feb. 22, 2021

Arbutus Biopharma Inc, Warminster, P

7. The Arbutus PD-L1 inhibitor ARB-272572 is a preclinical molecule that potently induces PD-L1 dimerization and internalization and demonstrates oral activity (10 mg/kg QD) in a humanized mouse model.…


 this content is exclusive to
Premium members

Unlock this content with a Premium membership to read it now.