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Sep. 18, 2021

GNE-149: A Monovalent Degrader and Full Antagonist of Estrogen Receptor Alpha

GNE-149

monovalent degrader + full antagonist of ER_ orally efficacious in xenograft model from ligand-based design of full antag. ACS Med. Chem. Lett., May 29, 2020 Genentech, South San Francisco, CA

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