TAS1553 Chemical Structure oral RNR subunit interaction inhibitor - Taiho Pharmaceutical Co., Ltd., Tsukuba, JP

oral RNR subunit interaction inhibitor

Ph. I candidate in oncology

HTS and SBDD

Commun. Biol.

Taiho Pharmaceutical Co., Ltd., Tsukuba, JP

Context. TAS1553 (Taiho Pharmaceutical) is an oral ribonucleotide reductase (RNR) inhibitor with antitumor activity. As the enzyme that catalyzes the rate-limiting step for deoxyribonucleotide triphosphate (dNTP) synthesis in cells,…


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