oral RNR subunit interaction inhibitor

Ph. I candidate in oncology

HTS and SBDD

Commun. Biol.

Taiho Pharmaceutical Co., Ltd., Tsukuba, JP

TAS1553 Chemical Structure oral RNR subunit interaction inhibitor - Taiho Pharmaceutical Co., Ltd., Tsukuba, JP

Context. TAS1553 (Taiho Pharmaceutical) is an oral ribonucleotide reductase (RNR) inhibitor with antitumor activity. As the enzyme that catalyzes the rate-limiting step for deoxyribonucleotide triphosphate (dNTP) synthesis in cells,…


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