BMS-986120
oral PAR4 antagonist Ph. II completed in thrombosis (discontinued) HTS, potency, and PK opt. J. Med. Chem. Bristol-Myers Squibb, Princeton, NJ
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acoramidis
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aficamten
The Cytokinetics next-generation myosin inhibitor, aficamten , is a phase II candidate for genetic hypertrophic cardiomyopathies, and is orally dosed between 5-30 mg QD. It follows BMS’s mavacamten ( acquired from Myokardia in a $13.1B deal), whose NDA is under review by the FDA. This class of molecules is intended to address hypertrophic [...]
PF-07328948
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BMS-986235/LAR-1219
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