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JNJ-54717793

Recent Publication

oral, BP, selective OX1R GPCR antagonist

orally efficacious in panic attack models

from optimization of internal OX2R antagonist

ACS Med. Chem. Lett., May 5, 2020

Janssen R&D, San Diego, CA

JNJ-54717793 is a selective antagonist of the orexin-1 receptor intended for use in anxiety disorders, in contrast to dual orexin-1/2 inhibitors and orexin-2 inhibitors typically applied for sleep disorders. It’s…

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JNJ-54717793

this content is exclusive to Premium members

this content is exclusive to
Premium members