© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
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oral, BP, selective OX1R GPCR antagonist
orally efficacious in panic attack models
from optimization of internal OX2R antagonist
ACS Med. Chem. Lett., May 5, 2020
Janssen R&D, San Diego, CA
JNJ-54717793 is a selective antagonist of the orexin-1 receptor intended for use in anxiety disorders, in contrast to dual orexin-1/2 inhibitors and orexin-2 inhibitors typically applied for sleep disorders. It’s…
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