potent, selective, oral FPR2 GPCR agonist
for heart failure prevent. / entered Ph. I in HV
from optimization of known ligand
J. Med. Chem., May 24, 2020
Kyorin Pharmaceutical / Bristol-Myers Squibb
BMS-986235/LAR-1219
BMS-986235/LAR-1219 is an FPR1-sparing FPR2-selective agonist intended to help resolve chronic inflammation/promote wound healing to prevent serious complications like heart failure. It’s a very efficient molecule and is orally efficacious…