BMS-986235-LAR-1219

potent, selective, oral FPR2 GPCR agonist

for heart failure prevent. / entered Ph. I in HV

from optimization of known ligand

J. Med. Chem., May 24, 2020

Kyorin Pharmaceutical / Bristol-Myers Squibb

BMS-986235/LAR-1219 is an FPR1-sparing FPR2-selective agonist intended to help resolve chronic inflammation/promote wound healing to prevent serious complications like heart failure. It’s a very efficient molecule and is orally efficacious…


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