PET ligand for brain O-GlcNAc hydrolase
stably visualized in human HV
discovery strategy undisclosed
Sci. Transl. Med., May 13, 2020
National Institutes of Health / Eli Lilly
[18F]LSN3316612
![structure of [18F]LSN3316612](https://drughunter.com/wp-content/uploads/2021/09/DHMOTM2020-05-07-18FLSN3316612.png)
[18F]LSN3316612 is a PET radiotracer for quantifying levels of O-GlcNAc hydrolase (OGA) in the brain. OGA is an enzyme involved in the post-translational modification of tau protein, and OGA…