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May 24, 2024

Synthetic Lethal USP1 Inhibitor for BRCA1/2-Mutant or HRD+ Cancers from Tango Therapeutics

TNG348

oral, reversible, allosteric USP1 inhibitor Ph. I/II in BRCA1/2 mutant or HRD+ solid tumors, terminated from known USP1 inhibitor ACS Spring 2024 Meeting First Time Disclosure Tango Therapeutics, Boston, MA

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