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DS69910557 chemical structure, oral hPTHR1 GPCR antagonist - Daiichi Sankyo, Tokyo, JP

DS69910557

Recent Publication

oral hPTHR1 GPCR antagonist

calcium-lowering activity in rodent

scaffold-hopping from lit. starting point

Bioorg. Med. Chem.

Daiichi Sankyo, Tokyo, JP

Context. DS69910557 (Daiichi Sankyo) is an oral inhibitor of parathyroid hormone (PTH) type 1 receptor (PTHR1) being developed as a calcium-lowering drug. The well-characterized secretin class receptor PTH1R is…


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