non-nucleotide STING agonist

novel mechanism for STING activation

from micromolar HTS hit

Nature

University of Texas Southwestern Medical Center, Dallas, TX

Compound 53 chemical structure, non-nucleotide STING agonist - University of Texas Southwestern Medical Center, Dallas, TX

Context. ”Compound 53” (University of Texas Southwestern Medical Center) is a stimulator of interferon (IFN) genes (STING) agonist. STING agonists have been heavily pursued in cancer immunology as increasing…


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