© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
New Drug Hunter content, featured events and job postings straight to your inbox. Trusted by >3,500 drug hunters worldwide, unsubscribe anytime.
<< Back to October
selective inhibitor of unphosphorylated HPK1
non-ATP competitive, IC50 = 1.2 µM
from 700k cmpd HTS for non-ATP comp. inh.
Janssen R&D, Spring House, PA
The Janssen non-ATP competitive HPK1 inhibitor, “compound 1,” was identified from a screening cascade specifically looking for allosteric inhibitors, which may provide a selectivity advantage over ATP-competitive starting points.…
Ask your company or librarian about a Drug Hunter membership to to see all summaries and get access to even more helpful information.