oral menin-MLL1 inhibitor

Ph. I/II candidate in leukemia

from HTS and SBDD

Mixed Lineage Leukemia 1 (MLL1)

Kura Oncology, San Diego, CA

Ziftomenib chemical structure oral menin-MLL1 inhibitor - Kura Oncology, San Diego, CA

Context. Ziftomenib (KO-539; MD Anderson) is an oral menin inhibitor being developed for mixed-lineage leukemia 1 (MLL1)-rearranged or NPM1-mutated acute myeloid leukemia (AML). Although a tumor suppressor in endocrine…


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