fbpx

molecules of the month

SR-717

non-nucleoside STING agonist

single agent systemic activity in I/O model

from 100k cmpd cellular pheno. screen + opt.

Science, Aug. 21, 2020

TSRI / Calibr, La Jolla, CA

Structure of non-nucleotide STING agonist SR-717
1 min read

SR-717 is STING agonist with a surprisingly similar mechanism to MSA-2, published contemporaneously with MSA-2. The identification of a second carboxylic acid-type molecule with both 2:1 binding stoichiometry and apparent tumor selectivity support both papers’ MoA hypotheses.


request a trial

Drug Hunter is commited to helping industry innovators make informed decisions. Premium members have access to our library of the latest stories in science, written by scientists.

Request a trial to access insights powering the pros in our industry.


already a member? log in: