QPX7728

serine and metallo-beta-lactamase inhibitor

oral activity in resistant infection model

from optimization of literature starting point

J. Med. Chem., Apr. 2, 2020

Qpex Biopharma, San Diego, CA

QPX7728 is an ultrabroad-spectrum beta-lactamase inhibitor with activity against both serine and zinc metallo-beta-lactamases, in contrast to approved beta-lactamase inhibitors such as relebactam which are only active against serine metalloproteases.…


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