oral p38α kinase inhibitor

Ph. II candidate in neurology

from SBDD and opt.

Nat. Commun.

EIP Pharma Inc, Boston, MA / Vertex, Cambridge, MA

Neflamapimod chemical structure oral p38α kinase inhibitor - EIP Pharma Inc, Boston, MA / Vertex, Cambridge, MA

Context. Neflamapimod (EIP Pharma, VX-745) is an oral, brain-penetrant p38α kinase inhibitor under development for neurodegenerative disorders. Among the roles of p38α MAPK is the activation of Rab5, a…


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