MRTX849

covalent KRASG12C inhibitor

in clinical development for KRASG12C+ cancers

from optimization of known starting point

J. Med. Chem., Apr. 6, 2020

Array / Mirati Therapeutics

April 2020’s molecule, the Mirati KRAS G12C inhibitor MRTX849, has been a hotly followed compound in development as it is the closest clinical KRAS inhibitor to the likely soon-to-be approved…


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