iclepertin structure

oral GlyT1 inhibitor

Ph. III candidate in schizophrenia

10 and 25 mg PO QD efficacy in CIAS improv.

J. Pharmacol. Exp. Ther.

Boehringer Ingelheim Pharma, Biberach an der Riss, DE

Context. Iclepertin (BI 425809; Boehringer Ingelheim) is an oral glycine transporter-1 (GlyT1) inhibitor being developed for cognitive impairment associated with schizophrenia (CIAS). The ineffectiveness of currently available antipsychotic medications…


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