dual _-opioid receptor agonist, _1 antagonist

oral analgesia w/ reduced opioid AEs, in Ph. I

from literature cmpd pharmacophore merging

J. Med. Chem., Oct. 16, 2020

ESTEVE Pharmaceuticals SA, Barcelona, ES

“EST73502” (ESTEVE oral dual mu-opioid receptor agonist, sigma-1 receptor antagonist clinical candidate)


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