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dual _-opioid receptor agonist, _1 antagonist
oral analgesia w/ reduced opioid AEs, in Ph. I
from literature cmpd pharmacophore merging
J. Med. Chem., Oct. 16, 2020
ESTEVE Pharmaceuticals SA, Barcelona, ES
“EST73502” (ESTEVE oral dual mu-opioid receptor agonist, sigma-1 receptor antagonist clinical candidate)
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