potent oral non-_-opioid receptor analgesic

oral activity in pain model, unknown mech.

Inspired by natural product, conolidine

Bioorg. Med. Chem., Aug. 8, 2020

Daiichi Sankyo, Tokyo, JP

DS34942424 is a potent oral analgesic discovered using the natural product conolidine as a starting point. While the authors were able to demonstrate that the compound does not exert its…


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