© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
New Drug Hunter content, featured events and job postings straight to your inbox. Trusted by >3,500 drug hunters worldwide, unsubscribe anytime.
<< Back to October
bioavailable bicyclic macrocycle PCSK9 inh.
%F cyno = 2.9, MW 1612, preclinical
from mRNA display screen and SBDD
Journal of Medicinal Chemistry
Merck & Co.
The Merck bicyclic macrocyclic peptide PCSK9 inhibitor, “compound 44,” is a highly potent (Ki = 0.00239 nM) and orally bioavailable (cyno %F = 2.9, t1/2 = 10 h) agent…
Ask your company or librarian about a Drug Hunter membership to to see all summaries and get access to even more helpful information.