potent pan-PIM kinase inhibitor
oral PD and efficacy in xenograft model
from SBDD of prior lead
Bioorg. Med. Chem. Lett., Oct. 14, 2020
Sanofi, Waltham/Cambridge, MA
“compound 27”
“compound 27” (Sanofi oral in vivo pan-PIM kinase inhibitor)
Drug Hunter