© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
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potent ghrelin receptor full agonist
for atrophy/cachexia, not advanced due to PK
from HTS and ligand-based design
J. Med. Chem., Aug. 12, 2020
Astrazeneca, Molndal, SE
“compound 12j” is a potent agonist of the ghrelin hormone receptor, activation of which stimulates growth hormone secretion and appetite among other activities. Ghrelin receptor antagonists have previously been explored…
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