oral prostaglandin F receptor GCPR antagonist

to treat IPF, in vivo efficacy in fibrosis model

from ~3M cmpd cell-based HTS and opt.

J. Med. Chem., Oct. 22, 2020 issue

Bayer AG, Wuppertal, DE

Structure of BAY-6672, a potent, selective and orally bioavailable prostanoid FP receptor antagonist

BAY-6672 (Bayer oral in vivo prostaglandin F receptor GCPR antagonist)


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