oral nonsteroidal MR antagonist

Ph. II candidate in DN and NASH (discontinued)

previous literature and hypothesis-driven opt.

J. Med. Chem.

Mitsubishi Tanabe Pharma Corporation, Yokohama, JP

Apararenone Chemical Structure oral nonsteroidal MR antagonist - Mitsubishi Tanabe Pharma Corporation, Yokohama, JP

Context. Apararenone (Mitsubishi Tanabe) is an oral nonsteroidal mineralocorticoid receptor (MR) antagonist. Agents with the ability to modulate the nuclear receptor MR have been pursued for at least 80…


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