Sudapyridine (WX-081) Chemical Structure, oral ATP-synthase inhibitor - WuXi AppTec, Shanghai, CN

oral ATP-synthase inhibitor

Ph. I candidate for pulmonary tuberculosis

toxicol. risk mitigation from prev. disclosed inhibitor

Bioorg. Med. Chem. Lett.

WuXi AppTec, Shanghai, CN

Context. Sudapyridine (WuXi AppTec) is an oral mycobacterial ATP synthase inhibitor being developed for tuberculosis (TB). Despite the significant success achieved with the discovery of antibiotic drugs in the…

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