oral Renin Inhibitor

Ph. III candidate in essential hypertension

SBDD and PK profile opt

J. Med. Chem.

Mitsubishi Tanabe, Yokohama, JPShanghai Pharmaceuticals, Shanghai, CN

SPH3127 chemical structure oral Renin Inhibitor - Mitsubishi Tanabe, Yokohama, JP Shanghai Pharmaceuticals, Shanghai, CN

Context. SPH3127 (Mitsubishi Tanabe and Shanghai Pharmaceuticals) is an oral direct renin inhibitor (DRI) being developed for hypertension. The renin-angiotensin-aldosterone system is responsible for regulating blood pressure. Existing drugs…


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