© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
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potent, non-oral CGRP antagonist
clean profile in 10-day rodent tox.
from SBDD of prior ligand
J. Med. Chem., Jul. 23, 2020
Sosei Heptares, Cambridge, UK
HTL22562 is a CGRP antagonist intended to treat acute migraines. Some prior oral CGRP antagonists failed in clinical trials due to liver tox. signals, so this program targeted a non-oral…
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