© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
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pre-systemic oral toll-like receptor 8 agonist
in multiple Ph. II studies for chron. hep. B
from optimization of lit. dual TLR7/8 agonists
J. Med. Chem., Jun. 3, 2020
Gilead Sciences, Foster City, CA
GS-9688 (selgantolimod) is a potent and selective TLR8 agonist sparing related receptor TLR7, and is intended to induce better immune responses in chronic hepatitis B. Since systemic activation of TLR8…
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