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oral prodrug of serine _-lactamase inh.
in dev. for multidrug resistant bact. infection
from optimization of prior _-lactamase inh.
J. Med. Chem., Jul. 24, 2020
Entasis Therapeutics, Waltham, MA
ETX0282 is an oral prodrug of a class A, C, and D serine β-lactamase inhibitor in clinical development for drug-resistant enterobacterial infections in combination with the beta-lactam drug cefpodoxime proxetil.…
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