4 minute read
Jun. 18, 2022

Dorzagliatin: A Dual-Acting Full Glucokinase (GK) Activator for Diabetes


oral allosteric glucokinase activator Ph. III candidate in T2DM HbA1c reduction vs placebo Journal of Diabetes Research, Jan 14, 2017 Hua Medicine, Shanghai, CN

Drug Hunter Team

Dorzagliatin (Hua Medicine) is an oral dual-acting full glucokinase (GK) activator being developed for type 2 diabetes . More than 50 years since the first report of the role of GK in glucose metabolism, no agents targeting this enzyme have been approved, although not for lack of trying. We recently covered a partial GK activator [...]



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