injectable OX2 agonist - Takeda

injectable OX2 agonist

Ph. I candidate for narcolepsy

from HTS and optimization

ACS Med. Chem. Lett.


Context. Danavorexton (Takeda, TAK-925) is a CNS-penetrant, injectable OX2 agonist. Orexin receptor (OX1/OX2) antagonists (e.g. daridorexant) are approved for treatment of insomnia. Orexin agonism would be expected to have…

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