© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
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brain penetrant AAK1 kinase inhibitor
efficacious in neuropathic pain model
from biochemical screen of in-house library
Journal of Medicinal Chemistry
Bristol Myers Squibb, Wallingford, US
The BMS AAK1 kinase inhibitor, compound 59, is brain-penetrant and acts on the CNS. The target was identified from a phenotypic screen of mouse knockouts, and a non-brain penetrant inhibitor…
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