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molecules of the month

“compound 25”-2

RORγt allosteric inhibitor

Orally bioavailable in higher species

from HTS and ligand-based design

ACS Med. Chem. Lett. 11, 114-119

Merck, Boston, MA

"compound 25"-2
1 min read

RORγt inhibitor from Merck (Merck ROR-gamma-t oral in vivo allosteric inhibitor)


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