RORγt allosteric inhibitor

Orally bioavailable in higher species

from HTS and ligand-based design

ACS Med. Chem. Lett. 11, 114-119

Merck, Boston, MA

"compound 25"-2

RORγt inhibitor from Merck (Merck ROR-gamma-t oral in vivo allosteric inhibitor)

get free samples and a Premium trial

Premium members get access to our library of hundreds of in-depth reviews on key molecules, ten new reviews each month, novel drug approval coverage, drug discovery company updates, and more: