© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
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class I sel. histone deacetylase (HDAC) inhib.
in vitro HIV reactivation for HIV eradication
from structure-based design of prior ligand
ACS Med. Chem. Lett., Jun. 22, 2020
Merck & Co., Kenilworth, NJ / West Point
“Compound 10” is a potent and selective inhibitor of Class I histone deacetylases (HDAC1/2/3) which increases HIV activity in treatment-suppressed patient immune cells for the goal of eradicating HIV from…
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